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Pharmacology

Title
Pharmacology
Semester
E2022
Master programme in
Medical biology * / Mathematical Bioscience * / Chemical Biology / Molecular Health Science
Type of activity

Course

Teaching language
English
Study regulation

Read about the Master Programme and find the Study Regulations at ruc.dk

Læs mere om uddannelsen og find din studieordning på ruc.dk

REGISTRATION AND STUDY ADMINISTRATIVE
Registration

Sign up for study activities at stads selvbetjeningwithin the announced registration period, as you can see on the Studyadministration homepage.

When signing up for study activities, please be aware of potential conflicts between study activities or exam dates.

The planning of activities at Roskilde University is based on the recommended study programs which do not overlap. However, if you choose optional courses and/or study plans that goes beyond the recommended study programs, an overlap of lectures or exam dates may occur depending on which courses you choose.

Number of participants
ECTS
5
Responsible for the activity
Louise Torp Dalgaard (ltd@ruc.dk)
Head of study
Lotte Jelsbak (ljelsbak@ruc.dk)
Teachers
Study administration
INM Studieadministration (inm-studieadministration@ruc.dk)
Exam code(s)
U60180
ACADEMIC CONTENT
Overall objective

This is a lecture-based course covering basic pharmacology and as well as the pharmacology of selected treatment areas. Basic pharmacology is introduced, such as receptor-ligand interactions, pharmacokinetics and dynamics, absorption, distribution, metabolism, secretion (ADME), as well as combination effects and adverse reactions.

The course also aims to give an introduction to development, clinical testing and registration of pharmacological compounds.

The pharmacology of selected areas of treatment is covered, for example cardiovascular pharmacology, renal pharmacology, chemotherapeutics, anti-inflammatory agents, hormones & hormone antagonists.

Detailed description of content

Pharmacology is a lecture based course that has the purpose to introduce students into basal pharmacology and how pharmaceteutics are used to treat the most common diseases and ailments.

The course will introduce how pharmaceuticals may act, are taken up, distributed in the body, metabolized in different tissues and how they are excreted.

Moreover, the course will teach students how drug candidates are developed and tested in order to be registered and approved for use in humans.

Course material and Reading list

Medical Pharmacology and Therapeutics, newest edition (6th edition), authors: Derek G. Waller, Anthony Sampson, Andrew Hitchings, Elsevier.

Overall plan and expected work effort
  • Lectures 30 hours

  • Preparation time 100 hours - this means that students should expect to use at least 6 hours of preparation time for each double-lecture throughout the semester.

  • Question hour 2 hour

  • Written exam 3 hour

  • In total 135 hours

Format
Evaluation and feedback

The course includes formative evaluation based on dialogue between the students and the teacher(s).

Students are expected to provide constructive critique, feedback and viewpoints during the course if it is needed for the course to have better quality. Every other year at the end of the course, there will also be an evaluation through a questionnaire in SurveyXact. The Study Board will handle all evaluations along with any comments from the course responsible teacher.

Furthermore, students can, in accordance with RUCs ‘feel free to state your views’ strategy through their representatives at the study board, send evaluations, comments or insights form the course to the study board during or after the course.

Programme

In the first part of the course, focus will be on basic pharmacology; how pharmaceutical drugs act in the organism, how they are taken up, distributed, metabolized and excreted.

The next part of the course has focus on how pharmaceutical drugs are developed, tested and approved for use as medicine.

The last part of the course has focus on introducing specific categories of pharmaceutical drugs that are in current use as medical substances. The course has focus on some of the most important diseases.

ASSESSMENT
Overall learning outcomes

After completing the course, the students will be able to:

  • describe the mechanisms involved in the organisms’ handling of foreign substances at different organiza-tional levels (cellular, tissue and organism levels)

  • explain the interaction of pharmaceuticals and foreign substances with biological membranes, including uptake, mechanism of action and metabolism in the organism as well as various tissue types

  • compare and discuss the pharmacological basis for treatment of selected, common diseases and describe actions and side effects of pharmacological agents

  • recall and describe how experiments and clinical studies have contributed to current knowledge and understanding of pharmacology and toxicology

  • compare the design and analysis of observational studies, clinical testing and experiments in the fields of pharmacology

  • interpret and evaluate pharmacological experiments, analyses and data in a biological context

  • conduct theoretical reviews of the latest scientific literature within pharmacology

  • propose and construct new scientific hypotheses as a starting point for a project related to pharmacology

  • communicate the knowledge and understanding gained from the course in a precise and scientific way.

Form of examination
Individual written invigilated exam.

The duration of the exam is 3 hours.

Permitted support and preparation materials for the exam: Dictionaries and non-programmable pocket calculator.


Assessment: 7-point grading scale.
Moderation: External examiner.
Form of Re-examination
Individual oral exam without time for preparation.

Time allowed for exam including time used for assessment: 20 minutes.

Permitted support and preparation materials: None.

Assessment: 7-point grading scale.
Moderation: External examiner.
Type of examination in special cases
Examination and assessment criteria

The exam is a 3 hr written invigilated exam. The exam has the form of posing general questions with essay answers.

Assessment criteria:

-Knowledge and understanding of pharmacological drug action, such as how drugs are taken up, metabolized in the organism and in individual tissues, and excreted. This includes describing the mechanisms involved in the organisms’ handling of foreign substances at different organizational levels (cellular, tissue and organism levels).

  • Knowledge about how drugs in general act on receptors as agonists and antagonists. Students should be able to explain the interaction of pharmaceuticals and foreign substances with biological membranes, including uptake, mechanism of action and metabolism in the organism as well as various tissue types

  • Knowledge about and understanding of how drug candidates undergo testing in order to obtain approval for use in human subjects. Students should be able to recall and describe how experiments and clinical studies have contributed to current knowledge and understanding of pharmacology and toxicology and how clinical pharmacological studies can be designed.

  • Knowledge and understanding of the pharmacological action of common drug categories used for treating common human disease. The student should be able to compare and discuss the pharmacological basis for treatment of selected, common diseases and describe actions and side effects of pharmacological agents.

  • Overall students must be able to demonstrate ability to interpret and evaluate pharmacological experiments, analyses and data in a biological context

Exam code(s)
Exam code(s) : U60180
Last changed 16/05/2022

lecture list:

Show lessons for Subclass: 1 Find calendar (1) PDF for print (1)

Wednesday 07-09-2022 10:15 - 07-09-2022 12:00 in week 36
Pharmacology (MHS)

Wednesday 14-09-2022 10:15 - 14-09-2022 12:00 in week 37
Pharmacology (MHS)

Wednesday 21-09-2022 10:15 - 21-09-2022 12:00 in week 38
Pharmacology (MHS)

Wednesday 28-09-2022 10:15 - 28-09-2022 12:00 in week 39
Pharmacology (MHS) - Room change due to NATDAG

Wednesday 05-10-2022 10:15 - 05-10-2022 12:00 in week 40
Pharmacology (MHS)

Wednesday 12-10-2022 10:15 - 12-10-2022 12:00 in week 41
Pharmacology (MHS)

Wednesday 19-10-2022 10:15 - 19-10-2022 12:00 in week 42
Pharmacology (MHS)

Wednesday 26-10-2022 10:15 - 26-10-2022 12:00 in week 43
Pharmacology (MHS)

Wednesday 02-11-2022 10:15 - 02-11-2022 12:00 in week 44
Pharmacology (MHS)

Wednesday 09-11-2022 10:15 - 09-11-2022 12:00 in week 45
Pharmacology (MHS)

Wednesday 16-11-2022 10:15 - 16-11-2022 12:00 in week 46
Pharmacology (MHS)

Wednesday 23-11-2022 10:15 - 23-11-2022 12:00 in week 47
Pharmacology (MHS)

Wednesday 30-11-2022 10:15 - 30-11-2022 12:00 in week 48
Pharmacology (MHS)

Wednesday 07-12-2022 10:15 - 07-12-2022 12:00 in week 49
Pharmacology (MHS)

Wednesday 07-12-2022 12:30 - 07-12-2022 13:45 in week 49
Guidance in sign-up for courses in the spring 2023 for students and MHS and CB

Wednesday 14-12-2022 10:15 - 14-12-2022 12:00 in week 50
Pharmacology (MHS)

Wednesday 21-12-2022 10:15 - 21-12-2022 12:00 in week 51
Pharmacology (MHS)

Wednesday 04-01-2023 10:00 - 04-01-2023 13:00 in week 01
Pharmacology - Exam (MHS)

Tuesday 14-02-2023 08:15 - 14-02-2023 16:00 in week 07
Pharmacology - Reexam (MHS)