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| Title |
Proteomics and Metabolomics
|
| Semester |
E2022
|
| Master programme in |
Chemistry * / Environmental Biology * / Chemical Biology / Molecular Health Science
|
| Type of activity |
Laboratory Course |
| Teaching language |
English
|
| Study regulation | |
| REGISTRATION AND STUDY ADMINISTRATIVE | |
| Registration |
Sign up for study activities at stads selvbetjeningwithin the announced registration period, as you can see on the Studyadministration homepage. When signing up for study activities, please be aware of potential conflicts between study activities or exam dates. The planning of activities at Roskilde University is based on the recommended study programs which do not overlap. However, if you choose optional courses and/or study plans that goes beyond the recommended study programs, an overlap of lectures or exam dates may occur depending on which courses you choose. |
| Number of participants |
The Master Programme/Institute reserves the right to cancel the course if fewer than 8 studentes are registered for the course. |
| ECTS |
5
|
| Responsible for the activity | |
| Head of study |
Anders Malmendal (amalm@ruc.dk)
|
| Teachers |
|
| Study administration |
INM Studieadministration (inm-studieadministration@ruc.dk)
|
| Exam code(s) |
U60046
|
| ACADEMIC CONTENT | |
| Overall objective |
Proteomics and metabolomics are used to profile large numbers of proteins and small molecule metabolites, respectively, within a cell, tissue, organ, or organism. This provides an overview of which biochemical processes that are affected and can provide new biological insights and unravel new hypotheses. These methods represent a shift in paradigm from hypothesis-driven studies where only one or a few compounds are measured. The aim of this course is to teach the students the principles of proteomics and metabolomics by mass spectrometry (MS) and NMR, and to make them acquainted with the practical steps involved in both types of analyses. |
| Detailed description of content |
The overall content of the course covers principles of proteomics and metabolomics by mass spectrometry and NMR. The students will be introduced to the following topics:
|
| Course material and Reading list |
Pensum in this course are lecture notes and articles provided during the course. |
| Overall plan and expected work effort |
- Total for this 5 ECTS course is 135 hours |
| Format |
|
| Evaluation and feedback |
The course includes formative evaluation based on dialogue between the students and the teacher(s). Students are expected to provide constructive critique, feedback and viewpoints during the course if it is needed for the course to have better quality. Every other year at the end of the course, there will also be an evaluation through a questionnaire in SurveyXact. The Study Board will handle all evaluations along with any comments from the course responsible teacher. Furthermore, students can, in accordance with RUCs ‘feel free to state your views’ strategy through their representatives at the study board, send evaluations, comments or insights form the course to the study board during or after the course. |
| Programme |
During the course there will be a series of lectures describing theoretical and practical aspects of proteomics and metabolomics. In parallel with this there will be a number of experimental sessions where samples will be prepared, experiments carried out and analysed, and biological conclusions being made. At the end of the course, groups of students will write manuscript-like reports based on experiments carried out during the course. |
| ASSESSMENT | |
| Overall learning outcomes |
After completing the course the student will be able to:
|
| Form of examination |
Individual oral exam based on a portfolio. The character limit of the portfolio is 12,000-36,000 characters, including spaces. Examples of written products are exercise responses, talking points for presentations, written feedback, reflections, written assignments. The preparation of the products may be subject to time limits. The character limits include the cover, table of contents, bibliography, figures and other illustrations, but exclude any appendices. Time allowed for exam including time used for assessment: 30 minutes. The assessment is an overall assessment of the written product(s) and the subsequent oral examination. Permitted support and preparation materials for the oral exam: Personal notes, own reports and assignments. Assessment: 7-point grading scale. Moderation: Internal co-assessor |
| Form of Re-examination |
Samme som ordinær eksamen / same form as ordinary exam
|
| Type of examination in special cases |
|
| Examination and assessment criteria |
Groups of students will write manuscript-like reports based on experiments carried out during the course. The individual oral exam will start with a presentation of the results described in the report. The assessment criteria regarding the written part:
The assessment of the oral exam is based on the student’s ability to meet the criteria mentioned above and their ability to
Furthermore, whether the performance meets all formal requirements The character limit of the portfolio is 12,000-36,000 characters, including spaces. The preparation of the products may be subject to time limits. The character limits include the cover, table of contents, bibliography, figures and other illustrations, but exclude any appendices. |
| Exam code(s) | |
| Last changed | 19/05/2022 |
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